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Sequence Detail
ID/Version
Q62018 Q3UY40 Q66JX4 Q8C9W7 Q8BND9 Q8BRD1 Q7TPS6 Q3UFF5 Q8C9Y3 Q8CHI1 (UniProt | EBI) Last sequence update: 2006-04-04
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=RNA polymerase-associated protein CTR9 homolog;AltName: Full=SH2 domain-binding protein 1;AltName: Full=Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa; Short=TPR-containing, SH2-binding phosphoprotein of 1
Provider SWISS-PROT
Sequence
Polypeptide 1173 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component 34 97 3 8
Sequence references in MGI J:32101 Malek SN, et al., p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains. J Biol Chem. 1996 Mar 22;271(12):6952-62
J:86755 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2002 Oct 31;9(5):179-88
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:149841 Ding L, et al., A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell. 2009 May 8;4(5):403-15
J:183965 Youn MY, et al., hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions. J Biol Chem. 2007 Nov 30;282(48):34727-34
J:237500 Osipovich AB, et al., Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation. Development. 2016 Dec 15;143(24):4595-4607
J:283190 Strikoudis A, et al., Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a. Nat Cell Biol. 2016 Nov;18(11):1127-1138
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory