Sequence Detail

ID/Version

Q61982 (UniProt | EBI)

Last sequence update: 1997-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Neurogenic locus notch homolog protein 3; Short=Notch 3;Contains: RecName: Full=Notch 3 extracellular truncation;Contains: RecName: Full=Notch 3 intracellular domain;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 2318 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Notch3	notch 3	55	152	3	30

Sequence references in MGI

J:18687 Lardelli M, et al., The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium. Mech Dev. 1994 May;46(2):123-36
J:88983 Wu L, et al., Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene. Gene. 2004 Mar 17;328:153-65
J:183220 Coleman ML, et al., Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor. J Biol Chem. 2007 Aug 17;282(33):24027-38
J:183961 Zheng X, et al., Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3368-73