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Sequence Detail
ID/Version
Q61554 Q60826 A2AQ53 (UniProt | EBI) Last sequence update: 2016-07-06
Last annotation update: 2019-05-08
Sequence
description
from provider
RecName: Full=Fibrillin-1 {ECO:0000250|UniProtKB:P35555};Contains: RecName: Full=Asprosin {ECO:0000250|UniProtKB:P35555};Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 2873 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Fbn1 fibrillin 1 35 10 8 19
Sequence references in MGI J:22526 Yin W, et al., Primary structure and developmental expression of Fbn-1, the mouse fibrillin gene. J Biol Chem. 1995 Jan 27;270(4):1798-806
J:110586 Carta L, et al., Fibrillins 1 and 2 perform partially overlapping functions during aortic development. J Biol Chem. 2006 Mar 24;281(12):8016-23
J:160041 Tsutsui K, et al., ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation. J Biol Chem. 2010 Feb 12;285(7):4870-82
J:165256 Nistala H, et al., Fibrillin-1 and -2 differentially modulate endogenous TGF-beta and BMP bioavailability during bone formation. J Cell Biol. 2010 Sep 20;190(6):1107-21
J:234498 Romere C, et al., Asprosin, a Fasting-Induced Glucogenic Protein Hormone. Cell. 2016 Apr 21;165(3):566-79
J:235251 Tiedemann K, et al., Fibrillin-1 directly regulates osteoclast formation and function by a dual mechanism. J Cell Sci. 2013 Sep 15;126(Pt 18):4187-94

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory