Sequence Detail

ID/Version

Q61501 Q80VZ3 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transcription factor E2F1 {ECO:0000303|PubMed:8114719}; Short=E2F-1 {ECO:0000303|PubMed:8114719};

Provider

SWISS-PROT

Sequence

Polypeptide 430 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	E2f1	E2F transcription factor 1	120	140	3	14

Sequence references in MGI

J:16907 Li Y, et al., Cloning, chromosomal location, and characterization of mouse E2F1. Mol Cell Biol. 1994 Mar;14(3):1861-9
J:42771 Dagnino L, et al., Expression patterns of the E2F family of transcription factors during mouse nervous system development. Mech Dev. 1997 Aug;66(1-2):13-25
J:72330 Porse BT, et al., E2f repression by c/ebpalpha is required for adipogenesis and granulopoiesis in vivo. Cell. 2001 Oct 19;107(2):247-58
J:89021 Holmberg C, et al., E2F-1-induced p53-independent apoptosis in transgenic mice. Oncogene. 1998 Jul 16;17(2):143-55
J:100168 Novy M, et al., EAPP, a novel E2F binding protein that modulates E2F-dependent transcription. Mol Biol Cell. 2005 May;16(5):2181-90
J:161707 Zaragoza K, et al., Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes. Mol Cell Biol. 2010 May;30(9):2293-304
J:279973 Zacksenhaus E, et al., A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity. Mol Cell Biol. 1993 Aug;13(8):4588-99
J:352393 Muller L, et al., Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling. Cell Rep. 2023 Jan 31;42(1):112031