Sequence Detail

ID/Version

Q61469 Q61690 Q8BPB8 Q6GT30 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Phospholipid phosphatase 1 {ECO:0000305}; EC=3.1.3.- {ECO:0000269|PubMed:10359651, ECO:0000269|PubMed:10620492, ECO:0000269|PubMed:10818444, ECO:0000269|PubMed:17379599}; EC=3.1.3.106 {ECO:0000269|PubMed:15461590, ECO:0000269

Provider

SWISS-PROT

Sequence

Polypeptide 283 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Plpp1	phospholipid phosphatase 1	85	99	3	32

Sequence references in MGI

J:28807 Egawa K, et al., Isolation of a novel ras-recision gene that is induced by hydrogen peroxide from a mouse osteoblastic cell line, MC3T3-E1. FEBS Lett. 1995 Sep 18;372(1):74-7
J:34520 Kai M, et al., Identification and cDNA cloning of 35-kDa phosphatidic acid phosphatase (type 2) bound to plasma membranes. Polymerase chain reaction amplification of mouse H2O2-inducible hic53 clone yielded the cDNA encoding phosphatidic acid phosphatase. J Biol Chem. 1996 Aug 2;271(31):18931-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:132439 Yue J, et al., Mice with transgenic overexpression of lipid phosphate phosphatase-1 display multiple organotypic deficits without alteration in circulating lysophosphatidate level. Cell Signal. 2004 Mar;16(3):385-99
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:149782 Tomsig JL, et al., Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid in vivo. Biochem J. 2009 May 1;419(3):611-8
J:282609 Zhao Y, et al., Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells. Biochem J. 2005 Jan 15;385(Pt 2):493-502
J:282680 Jasinska R, et al., Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate esters. Biochem J. 1999 Jun 15;340(3):677-86
J:282681 Nanjundan M, et al., Pulmonary lipid phosphate phosphohydrolase in plasma membrane signalling platforms. Biochem J. 2001 Sep 15;358(Pt 3):637-46
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89