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Sequence Detail
ID/Version
Q61451 Q61721 (UniProt | EBI) Last sequence update: 2007-01-23
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Leukocyte surface antigen CD53;AltName: Full=Cell surface glycoprotein CD53;AltName: CD_antigen=CD53;
Provider SWISS-PROT
Sequence
Polypeptide 219 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Cd53 CD53 antigen 24 100 3 9
Sequence references in MGI J:12638 Wright MD, et al., Gene structure, chromosomal localization, and protein sequence of mouse CD53 (Cd53): evidence that the transmembrane 4 superfamily arose by gene duplication. Int Immunol. 1993 Feb;5(2):209-16
J:203388 Liu QC, et al., Comparative expression profiling identifies differential roles for Myogenin and p38alpha MAPK signaling in myogenesis. J Mol Cell Biol. 2012 Dec;4(6):386-97
J:291776 Yeung L, et al., Leukocyte Tetraspanin CD53 Restrains alpha3 Integrin Mobilization and Facilitates Cytoskeletal Remodeling and Transmigration in Mice. J Immunol. 2020 Jul 15;205(2):521-532
J:294321 Greenberg ZJ, et al., The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling. J Immunol. 2020 Jan 1;204(1):58-67
J:338660 Demaria MC, et al., Tetraspanin CD53 Promotes Lymphocyte Recirculation by Stabilizing L-Selectin Surface Expression. iScience. 2020 May 22;23(5):101104

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory