Sequence Detail

ID/Version

Q61315 Q62044 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Adenomatous polyposis coli protein; Short=Protein APC; Short=mAPC;

Provider

SWISS-PROT

Sequence

Polypeptide 2845 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Apc	APC, WNT signaling pathway regulator	300	122	3	89

Sequence references in MGI

J:830 Su LK, et al., Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene [published erratum appears in Science 1992 May 22;256(5060):1114]. Science. 1992 May 1;256(5057):668-70
J:153333 Takizawa S, et al., Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli. Genes Cells. 2006 Apr;11(4):453-64
J:157023 Kawasaki Y, et al., The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice. EMBO Rep. 2009 Dec;10(12):1355-62
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89