Sequence Detail

ID/Version

Q61187 (UniProt | EBI)

Last sequence update: 1998-08-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Tumor susceptibility gene 101 protein;AltName: Full=ESCRT-I complex subunit TSG101;

Provider

SWISS-PROT

Sequence

Polypeptide 391 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tsg101	tumor susceptibility gene 101	90	101	4	18

Sequence references in MGI

J:32923 Li L, et al., Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells. Cell. 1996 May 3;85(3):319-29
J:51384 Wagner KU, et al., Genomic architecture and transcriptional activation of the mouse and human tumor susceptibility gene TSG101: common types of shorter transcripts are true alternative splice variants. Oncogene. 1998 Nov 26;17(21):2761-70
J:81304 Rountree MR, et al., DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet. 2000 Jul;25(3):269-77
J:85359 Masuhara M, et al., Enhanced degradation of MDM2 by a nuclear envelope component, mouse germ cell-less. Biochem Biophys Res Commun. 2003 Sep 5;308(4):927-32
J:164849 Jiao J, et al., Abnormal regulation of TSG101 in mice with spongiform neurodegeneration. Biochim Biophys Acta. 2009 Oct;1792(10):1027-35
J:224743 Lu Q, et al., TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7626-31
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89