Sequence Detail

ID/Version

Q61107 Q8VEC5 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Guanylate-binding protein 3; EC=3.6.5.- {ECO:0000269|PubMed:9659399};AltName: Full=GTP-binding protein 3; Short=GBP-3;AltName: Full=Guanine nucleotide-binding protein 3;

Provider

SWISS-PROT

Sequence

Polypeptide 620 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gbp3	guanylate binding protein 3	43	96	7	9

Sequence references in MGI

J:48603 Han BH, et al., Cloning, expression, and characterization of a novel guanylate-binding protein, GBP3 in murine erythroid progenitor cells. Biochim Biophys Acta. 1998 May 19;1384(2):373-86
J:155210 Degrandi D, et al., Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense. J Immunol. 2007 Dec 1;179(11):7729-40
J:208845 Pilla DM, et al., Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS. Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):6046-51
J:210626 Meunier E, et al., Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. Nature. 2014 May 15;509(7500):366-70
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89