Sequence Detail

ID/Version

Q61102 Q3U7S8 A2AC46 (UniProt | EBI)

Last sequence update: 2011-06-28
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Iron-sulfur clusters transporter ABCB7, mitochondrial {ECO:0000305};AltName: Full=ATP-binding cassette sub-family B member 7, mitochondrial;AltName: Full=ATP-binding cassette transporter 7; Short=ABC transporter 7 protein;Flags: Prec

Provider

SWISS-PROT

Sequence

Polypeptide 752 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Abcb7	ATP-binding cassette, sub-family B member 7	53	102	3	5

Sequence references in MGI

J:39831 Savary S, et al., Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human. Genomics. 1997 Apr 15;41(2):275-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:105934 Clarke SL, et al., Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S cluster. EMBO J. 2006 Feb 8;25(3):544-53
J:106838 Pondarre C, et al., The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis. Hum Mol Genet. 2006 Mar 15;15(6):953-64
J:136594 Pondarre C, et al., Abcb7, the gene responsible for X-linked sideroblastic anemia with ataxia, is essential for hematopoiesis. Blood. 2007 Apr 15;109(8):3567-9
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:304585 Maio N, et al., Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis. Haematologica. 2019 Sep;104(9):1756-1767