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Sequence Detail
Q61072 Q80U94 E9QPP2 Q61853 Q60618 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2018-05-23
from provider
RecName: Full=Disintegrin and metalloproteinase domain-containing protein 9; Short=ADAM 9; EC=3.4.24.-;AltName: Full=Meltrin-gamma;AltName: Full=Metalloprotease/disintegrin/cysteine-rich protein 9;AltName: Full=Myeloma cell metalloproteina
Polypeptide 845 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Adam9 a disintegrin and metallopeptidase domain 9 (meltrin gamma) 50 4 8 8
Sequence references in MGI J:30468 Weskamp G, et al., A family of cellular proteins related to snake venom disintegrins. Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2748-51
J:30529 Yagami-Hiromasa T, et al., A metalloprotease-disintegrin participating in myoblast fusion [see comments]. Nature. 1995 Oct 19;377(6550):652-6
J:31451 Weskamp G, et al., MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains. J Cell Biol. 1996 Feb;132(4):717-26
J:74655 Weskamp G, et al., Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life. Mol Cell Biol. 2002 Mar;22(5):1537-44
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:113785 Howard L, et al., Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1. J Biol Chem. 1999 Oct 29;274(44):31693-9
J:143698 Roghani M, et al., Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. J Biol Chem. 1999 Feb 5;274(6):3531-40
J:148993 Guaiquil V, et al., ADAM9 is involved in pathological retinal neovascularization. Mol Cell Biol. 2009 May;29(10):2694-703
J:150865 Parry DA, et al., Loss of the metalloprotease ADAM9 leads to cone-rod dystrophy in humans and retinal degeneration in mice. Am J Hum Genet. 2009 May;84(5):683-91
J:222585 Wong E, et al., The Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site. J Biol Chem. 2015 May 8;290(19):12135-46
J:233591 Nath D, et al., Meltrin gamma(ADAM-9) mediates cellular adhesion through alpha(6)beta(1 )integrin, leading to a marked induction of fibroblast cell motility. J Cell Sci. 2000 Jun;113 ( Pt 12):2319-28

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last database update
MGI 6.12
The Jackson Laboratory