Sequence Detail

ID/Version

Q61010 Q8C2H2 Q3TER5 Q9ER09 (UniProt | EBI)

Last sequence update: 2003-09-26
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase DTX1; EC=2.3.2.27 {ECO:0000269|PubMed:15684388};AltName: Full=FXI-T1;AltName: Full=Protein deltex-1; Short=Deltex1; Short=mDTX1;AltName: Full=RING-type E3 ubiquitin transferase DTX1 {ECO:00

Provider

SWISS-PROT

Sequence

Polypeptide 627 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dtx1	deltex 1, E3 ubiquitin ligase	39	108	3	21

Sequence references in MGI

J:35307 Pampeno CL, et al., A novel cDNA transcript expressed in fractionated X-irradiation-induced murine thymomas. Cell Growth Differ. 1996 Aug;7(8):1113-23
J:68965 Kishi N, et al., Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis. Int J Dev Neurosci. 2001 Feb;19(1):21-35
J:73301 Mitsiadis TA, et al., Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression. Mech Dev. 2001 Dec;109(2):399-403
J:95987 Liu WH, et al., Deltex regulates T-cell activation by targeted degradation of active MEKK1. Mol Cell Biol. 2005 Feb;25(4):1367-78
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563