Sequence Detail

ID/Version

Q60989 O08865 A2BGY6 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase XIAP; EC=2.3.2.27 {ECO:0000250|UniProtKB:P98170};AltName: Full=Baculoviral IAP repeat-containing protein 4;AltName: Full=IAP homolog A {ECO:0000303|PubMed:8643514};AltName: Full=Inhibitor of apoptosis prot

Provider

SWISS-PROT

Sequence

Polypeptide 496 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Xiap	X-linked inhibitor of apoptosis	48	106	4	53

Sequence references in MGI

J:33039 Uren AG, et al., Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Proc Natl Acad Sci U S A. 1996 May 14;93(10):4974-8
J:153190 Van Themsche C, et al., X-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalization. J Biol Chem. 2009 Jul 31;284(31):20462-6
J:199466 Fuchs Y, et al., Sept4/ARTS regulates stem cell apoptosis and skin regeneration. Science. 2013 Jul 19;341(6143):286-9
J:269496 Koren E, et al., ARTS mediates apoptosis and regeneration of the intestinal stem cell niche. Nat Commun. 2018 Nov 2;9(1):4582
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89