Sequence Detail

ID/Version

Q60854 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Serpin B6;AltName: Full=Placental thrombin inhibitor;AltName: Full=Proteinase inhibitor 6; Short=PI-6;

Provider

SWISS-PROT

Sequence

Polypeptide 378 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Serpinb6a	serine (or cysteine) peptidase inhibitor, clade B, member 6a	17	107	7	14

Sequence references in MGI

J:26852 Sun J, et al., Gene structure, chromosomal localization, and expression of the murine homologue of human proteinase inhibitor 6 (PI-6) suggests divergence of PI-6 from the ovalbumin serpins. J Biol Chem. 1995 Jul 7;270(27):16089-96
J:164861 Scott FL, et al., SerpinB6 is an inhibitor of kallikrein-8 in keratinocytes. J Biochem. 2007 Oct;142(4):435-42
J:164931 Sirmaci A, et al., A truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing loss. Am J Hum Genet. 2010 May 14;86(5):797-804
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89