Sequence Detail

ID/Version

Q60806 Q9R009 Q60822 (UniProt | EBI)

Last sequence update: 2001-04-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Serine/threonine-protein kinase PLK3; EC=2.7.11.21;AltName: Full=Cytokine-inducible serine/threonine-protein kinase;AltName: Full=FGF-inducible kinase;AltName: Full=Polo-like kinase 3; Short=PLK-3;

Provider

SWISS-PROT

Sequence

Polypeptide 631 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Plk3	polo like kinase 3	75	100	3	24

Sequence references in MGI

J:24944 Donohue PJ, et al., Identification by targeted differential display of an immediate early gene encoding a putative serine/threonine kinase. J Biol Chem. 1995 Apr 28;270(17):10351-7
J:136425 Yang Y, et al., Polo-like kinase 3 functions as a tumor suppressor and is a negative regulator of hypoxia-inducible factor-1 alpha under hypoxic conditions. Cancer Res. 2008 Jun 1;68(11):4077-85
J:147768 Horner TJ, et al., Stimulation of polo-like kinase 3 mRNA decay by tristetraprolin. Mol Cell Biol. 2009 Apr;29(8):1999-2010
J:175096 Myer DL, et al., Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors. Mutat Res. 2011 Sep 1;714(1-2):1-10
J:178436 Xu D, et al., Regulation of PTEN stability and activity by Plk3. J Biol Chem. 2010 Dec 17;285(51):39935-42