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Sequence Detail
ID/Version
Q60806 Q60822 Q9R009 (UniProt | EBI) Last sequence update: 2001-04-27
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Serine/threonine-protein kinase PLK3; EC=2.7.11.21;AltName: Full=Cytokine-inducible serine/threonine-protein kinase;AltName: Full=FGF-inducible kinase;AltName: Full=Polo-like kinase 3; Short=PLK-3;
Provider SWISS-PROT
Sequence
Polypeptide 631 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Plk3 polo like kinase 3 60 100 3 24
Sequence references in MGI J:24944 Donohue PJ, et al., Identification by targeted differential display of an immediate early gene encoding a putative serine/threonine kinase. J Biol Chem. 1995 Apr 28;270(17):10351-7
J:136425 Yang Y, et al., Polo-like kinase 3 functions as a tumor suppressor and is a negative regulator of hypoxia-inducible factor-1 alpha under hypoxic conditions. Cancer Res. 2008 Jun 1;68(11):4077-85
J:147768 Horner TJ, et al., Stimulation of polo-like kinase 3 mRNA decay by tristetraprolin. Mol Cell Biol. 2009 Apr;29(8):1999-2010
J:175096 Myer DL, et al., Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors. Mutat Res. 2011 Sep 1;714(1-2):1-10
J:178436 Xu D, et al., Regulation of PTEN stability and activity by Plk3. J Biol Chem. 2010 Dec 17;285(51):39935-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory