Sequence Detail

ID/Version

Q60751 O70438 Q62123 (UniProt | EBI)

Last sequence update: 2001-01-11
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Insulin-like growth factor 1 receptor; EC=2.7.10.1;AltName: Full=Insulin-like growth factor I receptor; Short=IGF-I receptor;AltName: CD_antigen=CD221;Contains: RecName: Full=Insulin-like growth factor 1 receptor alpha chain

Provider

SWISS-PROT

Sequence

Polypeptide 1373 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Igf1r	insulin-like growth factor I receptor	150	137	4	27

Sequence references in MGI

J:15108 Liu JP, et al., Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell. 1993 Oct 8;75(1):59-72
J:15430 Wada J, et al., Cloning of cDNA for the alpha subunit of mouse insulin-like growth factor I receptor and the role of the receptor in metanephric development. Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10360-4
J:22689 Wilks AF, et al., The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family. Gene. 1989 Dec 21;85(1):67-74
J:233169 Osorio FG, et al., Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling. Nat Med. 2016 Jan;22(1):91-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89