Sequence Detail

ID/Version

Q60749 Q99M33 A2ACH3 Q7M4N5 Q60735 B2KG38 Q3U8T3 (UniProt | EBI)

Last sequence update: 2005-04-12
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 1;AltName: Full=GAP-associated tyrosine phosphoprotein p62;AltName: Full=Src-associated in mitosis 68 kDa protein; Short=Sam68;AltName: Full=p21 Ras GTPase-act

Provider

SWISS-PROT

Sequence

Polypeptide 443 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	56	106	4	35

Sequence references in MGI

J:17885 Fumagalli S, et al., A target for Src in mitosis. Nature. 1994 Apr 28;368(6474):871-4
J:26499 Agger R, et al., Purification and cDNA sequence of a murine protein homologous to the human p62 tyrosine phosphoprotein that associates with the Ras GTPase-activating protein p120 GAP. Gene. 1995 Jun 9;158(2):307-8
J:41194 Richard S, et al., Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1. Mol Cell Biol. 1995 Jan;15(1):186-97
J:53497 Di Fruscio M, et al., Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2710-5
J:80589 Hong W, et al., Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68. Mol Cancer Res. 2002 Nov;1(1):48-55
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113665 Chen T, et al., Self-association of the single-KH-domain family members Sam68, GRP33, GLD-1, and Qk1: role of the KH domain. Mol Cell Biol. 1997 Oct;17(10):5707-18
J:113965 Cote J, et al., Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1. Mol Biol Cell. 2003 Jan;14(1):274-87
J:179373 Iijima T, et al., SAM68 Regulates Neuronal Activity-Dependent Alternative Splicing of Neurexin-1. Cell. 2011 Dec 23;147(7):1601-14
J:199861 Ehrmann I, et al., The tissue-specific RNA binding protein T-STAR controls regional splicing patterns of neurexin pre-mRNAs in the brain. PLoS Genet. 2013 Apr;9(4):e1003474
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:208331 Iijima T, et al., Neuronal cell type-specific alternative splicing is regulated by the KH domain protein SLM1. J Cell Biol. 2014 Feb 3;204(3):331-42
J:230391 Elliott DJ, et al., A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection. Proc Natl Acad Sci U S A. 2000 May 23;97(11):5717-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87