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Sequence Detail
Q60722 Q62211 Q64072 Q80UE8 Q60721 (UniProt | EBI) Last sequence update: 1996-11-01
Last annotation update: 2019-05-08
from provider
RecName: Full=Transcription factor 4; Short=TCF-4;AltName: Full=Class A helix-loop-helix transcription factor ME2;AltName: Full=Immunoglobulin transcription factor 2; Short=ITF-2; Short=MITF-2;AltName: Full=SL3-3 enhancer factor 2;
Polypeptide 670 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Tcf4 transcription factor 4 60 16 6 33
Sequence references in MGI J:20051 Soosaar A, et al., Expression of basic-helix-loop-helix transcription factor ME2 during brain development and in the regions of neuronal plasticity in the adult brain. Brain Res Mol Brain Res. 1994 Aug;25(1-2):176-80
J:31425 Skerjanc IS, et al., A splice variant of the ITF-2 transcript encodes a transcription factor that inhibits MyoD activity. J Biol Chem. 1996 Feb 16;271(7):3555-61
J:38018 Pscherer A, et al., The helix-loop-helix transcription factor SEF-2 regulates the activity of a novel initiator element in the promoter of the human somatostatin receptor II gene. EMBO J. 1996 Dec 2;15(23):6680-90
J:54634 Dorflinger U, et al., Activation of somatostatin receptor II expression by transcription factors MIBP1 and SEF-2 in the murine brain. Mol Cell Biol. 1999 May;19(5):3736-47
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:134786 Ravanpay AC, et al., E protein dosage influences brain development more than family member identity. J Neurosci Res. 2008 May 15;86(7):1472-81

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory