Sequence Detail

ID/Version

Q60716 Q8VBU4 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Prolyl 4-hydroxylase subunit alpha-2; Short=4-PH alpha-2; EC=1.14.11.2 {ECO:0000269|PubMed:7753822};AltName: Full=Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 537 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide	15	100	3	9

Sequence references in MGI

J:25202 Helaakoski T, et al., Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit. Proc Natl Acad Sci U S A. 1995 May 9;92(10):4427-31
J:72211 Nokelainen M, et al., Characterization of the human and mouse genes for the alpha subunit of type II prolyl 4-hydroxylase Identification of a previously unknown alternatively spliced exon and its expression in various tissues. Eur J Biochem. 2001 Oct;268(20):5300-9
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89