Sequence Detail

ID/Version

Q60714 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Long-chain fatty acid transport protein 1 {ECO:0000305};AltName: Full=Arachidonate--CoA ligase; EC=6.2.1.15 {ECO:0000269|PubMed:10593920, ECO:0000269|PubMed:12235169, ECO:0000269|PubMed:12937175};AltName: Full=Fatty acid transport pr

Provider

SWISS-PROT

Sequence

Polypeptide 646 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	92	103	4	11

Sequence references in MGI

J:21397 Schaffer JE, et al., Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein [see comments]. Cell. 1994 Nov 4;79(3):427-36
J:42634 Hirsch D, et al., A family of fatty acid transporters conserved from mycobacterium to man. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8625-9
J:50347 Hui TY, et al., Characterization of the murine fatty acid transport protein gene and its insulin response sequence. J Biol Chem. 1998 Oct 16;273(42):27420-9
J:82590 Richards MR, et al., Oligomerization of the murine fatty acid transport protein 1. J Biol Chem. 2003 Mar 21;278(12):10477-83
J:88657 Kim JK, et al., Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle. J Clin Invest. 2004 Mar;113(5):756-63
J:217345 Guitart M, et al., Fatty acid transport protein 1 (FATP1) localizes in mitochondria in mouse skeletal muscle and regulates lipid and ketone body disposal. PLoS One. 2014;9(5):e98109
J:244749 Arif A, et al., EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice. Nature. 2017 Feb 16;542(7641):357-361
J:261158 Hatch GM, et al., FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells. J Lipid Res. 2002 Sep;43(9):1380-9
J:261159 Coe NR, et al., The fatty acid transport protein (FATP1) is a very long chain acyl-CoA synthetase. J Biol Chem. 1999 Dec 17;274(51):36300-4
J:276398 DiRusso CC, et al., Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast. J Biol Chem. 2005 Apr 29;280(17):16829-37
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89