Sequence Detail

ID/Version

Q60676 G5E819 O35299 (UniProt | EBI)

Last sequence update: 2013-10-16
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Serine/threonine-protein phosphatase 5; Short=PP5; EC=3.1.3.16 {ECO:0000269|PubMed:21994940};AltName: Full=Protein phosphatase T; Short=PPT;

Provider

SWISS-PROT

Sequence

Polypeptide 499 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ppp5c	protein phosphatase 5, catalytic subunit	42	96	3	25

Sequence references in MGI

J:21536 Chinkers M, Targeting of a distinctive protein-serine phosphatase to the protein kinase-like domain of the atrial natriuretic peptide receptor. Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11075-9
J:122564 Yong W, et al., Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest. J Biol Chem. 2007 May 18;282(20):14690-4
J:177167 Tomsig JL, et al., Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif. J Biol Chem. 2003 Mar 21;278(12):10048-54
J:178732 Hinds TD Jr, et al., Protein Phosphatase 5 Mediates Lipid Metabolism through Reciprocal Control of Glucocorticoid Receptor and Peroxisome Proliferator-activated Receptor-gamma (PPARgamma). J Biol Chem. 2011 Dec 16;286(50):42911-22
J:186454 Grankvist N, et al., Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse pancreatic islets and clonal MIN6 cells. Diabetologia. 2012 Jul;55(7):2005-15
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89