Sequence Detail

ID/Version

Q60664 Q7TMU8 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=Inositol 1,4,5-triphosphate receptor associated 2 {ECO:0000305};AltName: Full=Lymphoid-restricted membrane protein;AltName: Full=Protein Jaw1;Contains: RecName: Full=Processed inositol 1,4,5-triphosphate receptor associated 2;

Provider

SWISS-PROT

Sequence

Polypeptide 539 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Irag2	inositol 1,4,5-triphosphate receptor associated 2	22	98	3	19

Sequence references in MGI

J:35495 Behrens TW, et al., Carboxyl-terminal targeting and novel post-translational processing of JAW1, a lymphoid protein of the endoplasmic reticulum. J Biol Chem. 1996 Sep 20;271(38):23528-34
J:35633 Behrens TW, et al., Jaw1, A lymphoid-restricted membrane protein localized to the endoplasmic reticulum. J Immunol. 1994 Jul 15;153(2):682-90
J:203403 Shindo Y, et al., Lrmp/Jaw1 is expressed in sweet, bitter, and umami receptor-expressing cells. Chem Senses. 2010 Feb;35(2):171-7
J:287130 Kozono T, et al., Jaw1/LRMP has a role in maintaining nuclear shape via interaction with SUN proteins. J Biochem. 2018 Oct 1;164(4):303-311
J:292477 Peters CH, et al., Isoform-specific regulation of HCN4 channels by a family of endoplasmic reticulum proteins. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):18079-18090
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89