Sequence Detail

ID/Version

Q60636 A2VDE8 Q3UET9 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=PR domain zinc finger protein 1; EC=2.1.1.-;AltName: Full=B lymphocyte-induced maturation protein 1; Short=Blimp-1;AltName: Full=Beta-interferon gene positive regulatory domain I-binding factor;AltName: Full=PR domain-contain

Provider

SWISS-PROT

Sequence

Polypeptide 856 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prdm1	PR domain containing 1, with ZNF domain	84	135	4	34

Sequence references in MGI

J:17825 Turner CA Jr, et al., Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell. 1994 Apr 22;77(2):297-306
J:66441 Tunyaplin C, et al., Characterization of the B lymphocyte-induced maturation protein-1 (Blimp-1) gene, mRNA isoforms and basal promoter. Nucleic Acids Res. 2000 Dec 15;28(24):4846-55
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:109626 Ancelin K, et al., Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nat Cell Biol. 2006 Jun;8(6):623-30
J:153979 Morgan MA, et al., Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation. Mol Cell Biol. 2009 Nov;29(21):5813-27
J:232474 Mackay LK, et al., Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes. Science. 2016 Apr 22;352(6284):459-63
J:303193 Jeong E, et al., Early estrogen-induced gene 1 facilitates osteoclast formation through the inhibition of interferon regulatory factor 8 expression. FASEB J. 2020 Sep;34(9):12894-12906