Sequence Detail

ID/Version

Q60603 Q3USQ9 Q32MR6 (UniProt | EBI)

Last sequence update: 2016-11-30
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Voltage-gated delayed rectifier potassium channel KCNH1 {ECO:0000305};AltName: Full=Ether-a-go-go potassium channel 1 {ECO:0000250|UniProtKB:O95259}; Short=EAG channel 1 {ECO:0000250|UniProtKB:O95259}; Short=m-eag {ECO:000030

Provider

SWISS-PROT

Sequence

Polypeptide 989 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	86	98	4	8

Sequence references in MGI

J:18517 Warmke JW, et al., A family of potassium channel genes related to eag in Drosophila and mammals. Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3438-42
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:188709 Ninkovic M, et al., Physical and functional interaction of K(V)10.1 with Rabaptin-5 impacts ion channel trafficking. FEBS Lett. 2012 Sep 21;586(19):3077-84
J:198153 Ufartes R, et al., Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice. Hum Mol Genet. 2013 Jun 1;22(11):2247-62
J:199696 Marques-Carvalho MJ, et al., Structural, biochemical, and functional characterization of the cyclic nucleotide binding homology domain from the mouse EAG1 potassium channel. J Mol Biol. 2012 Oct 12;423(1):34-46
J:217991 Brelidze TI, et al., Absence of direct cyclic nucleotide modulation of mEAG1 and hERG1 channels revealed with fluorescence and electrophysiological methods. J Biol Chem. 2009 Oct 9;284(41):27989-97
J:245886 Mortensen LS, et al., KV 10.1 opposes activity-dependent increase in Ca(2)(+) influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse. J Physiol. 2015 Jan 1;593(1):181-96
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89