Sequence Detail

ID/Version

Q5U4E0 Q5DTS1 Q8BQU2 (UniProt | EBI)

Last sequence update: 2004-12-07
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=LHFPL tetraspan subfamily member 4 protein {ECO:0000250|UniProtKB:Q7Z7J7};AltName: Full=GABAA receptor regulatory Lhfpl4 {ECO:0000303|PubMed:28279354};AltName: Full=Lipoma HMGIC fusion partner-like 4 protein {ECO:0000312|MGI:MGI:3057108};

Provider

SWISS-PROT

Sequence

Polypeptide 247 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lhfpl4	lipoma HMGIC fusion partner-like protein 4	31	97	4	10

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:241136 Zhao F, et al., Novel function of LHFPL2 in female and male distal reproductive tract development. Sci Rep. 2016 Mar 11;6:23037
J:254795 Davenport EC, et al., An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors. Cell Rep. 2017 Oct 3;21(1):70-83
J:256156 Yamasaki T, et al., GARLH Family Proteins Stabilize GABAA Receptors at Synapses. Neuron. 2017 Mar 8;93(5):1138-1152.e6
J:265620 Wu M, et al., Impairment of Inhibitory Synapse Formation and Motor Behavior in Mice Lacking the NL2 Binding Partner LHFPL4/GARLH4. Cell Rep. 2018 May 8;23(6):1691-1705
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89