Sequence Detail

ID/Version

Q5SVQ0 Q5SVQ3 Q5SVQ2 Q6PGC6 Q5SVQ7 Q80Y65 Q5SVQ1 (UniProt | EBI)

Last sequence update: 2004-12-21
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Histone acetyltransferase KAT7 {ECO:0000305}; EC=2.3.1.48 {ECO:0000305|PubMed:21149574};AltName: Full=Histone acetyltransferase binding to ORC1 {ECO:0000303|PubMed:23319590};AltName: Full=Lysine acetyltransferase 7;AltName: Full=MOZ,

Provider

SWISS-PROT

Sequence

Polypeptide 613 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kat7	K(lysine) acetyltransferase 7	132	110	4	143

Sequence references in MGI

J:170405 Kueh AJ, et al., HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development. Mol Cell Biol. 2011 Feb;31(4):845-60
J:177092 Mishima Y, et al., The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis. Blood. 2011 Sep 1;118(9):2443-53
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:284983 MacPherson L, et al., HBO1 is required for the maintenance of leukaemia stem cells. Nature. 2020 Jan;577(7789):266-270
J:285029 Newman DM, et al., Essential role for the histone acetyltransferase KAT7 in T cell development, fitness, and survival. J Leukoc Biol. 2017 Apr;101(4):887-892
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89