Sequence Detail

ID/Version

Q5SRY7 Q8K022 Q923H0 Q3TLZ8 Q3TGM9 Q8BY90 (UniProt | EBI)

Last sequence update: 2004-12-21
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=F-box/WD repeat-containing protein 11;AltName: Full=F-box and WD repeats protein beta-TrCP2;AltName: Full=F-box/WD repeat-containing protein 1B;AltName: Full=Homologous to Slimb protein {ECO:0000303|PubMed:11896578}; Short=HOS {ECO:0

Provider

SWISS-PROT

Sequence

Polypeptide 542 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fbxw11	F-box and WD-40 domain protein 11	55	100	4	58

Sequence references in MGI

J:75267 Bhatia N, et al., Mouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaB. Oncogene. 2002 Feb 28;21(10):1501-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:166433 Ohsaki K, et al., The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2. J Biochem. 2008 Nov;144(5):609-18
J:209489 Shirogane T, et al., SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein. J Biol Chem. 2005 Jul 22;280(29):26863-72