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Sequence Detail
ID/Version
Q5SRY7 Q8BY90 Q923H0 Q3TGM9 Q3TLZ8 Q8K022 (UniProt | EBI) Last sequence update: 2004-12-21
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=F-box/WD repeat-containing protein 11;AltName: Full=F-box and WD repeats protein beta-TrCP2;AltName: Full=F-box/WD repeat-containing protein 1B;AltName: Full=Homologous to Slimb protein {ECO:0000303|PubMed:11896578}; Short=HOS {ECO:0
Provider SWISS-PROT
Sequence
Polypeptide 542 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Fbxw11 F-box and WD-40 domain protein 11 51 99 4 57
Sequence references in MGI J:75267 Bhatia N, et al., Mouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaB. Oncogene. 2002 Feb 28;21(10):1501-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:166433 Ohsaki K, et al., The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2. J Biochem. 2008 Nov;144(5):609-18
J:209489 Shirogane T, et al., SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein. J Biol Chem. 2005 Jul 22;280(29):26863-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory