Sequence Detail

ID/Version

Q5RKZ7 B7ZWI5 Q8R058 Q9JL32 Q9JL33 B2RVW8 (UniProt | EBI)

Last sequence update: 2009-04-14
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Molybdenum cofactor biosynthesis protein 1;Includes: RecName: Full=GTP 3',8-cyclase; EC=4.1.99.22 {ECO:0000250|UniProtKB:P69848}; AltName: Full=Molybdenum cofactor biosynthesis protein A;Includes: RecName: Full=Cyclic pyranopter

Provider

SWISS-PROT

Sequence

Polypeptide 636 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mocs1	molybdenum cofactor synthesis 1	31	96	3	4

Sequence references in MGI

J:66677 Gray TA, et al., Diverse splicing mechanisms fuse the evolutionarily conserved bicistronic MOCS1A and MOCS1B open reading frames. RNA. 2000 Jul;6(7):928-36
J:80807 Lee HJ, et al., Molybdenum cofactor-deficient mice resemble the phenotype of human patients. Hum Mol Genet. 2002 Dec 15;11(26):3309-17
J:98026 Reiss J, et al., The pathogenesis of molybdenum cofactor deficiency, its delay by maternal clearance, and its expression pattern in microarray analysis. Mol Genet Metab. 2005 May;85(1):12-20
J:125242 Kugler S, et al., Long-term rescue of a lethal inherited disease by adeno-associated virus-mediated gene transfer in a mouse model of molybdenum-cofactor deficiency. Am J Hum Genet. 2007 Feb;80(2):291-7
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89