Sequence Detail

ID/Version

Q5RJI4 Q8VBZ6 B6F136 Q3UZD3 (UniProt | EBI)

Last sequence update: 2010-03-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Extracellular tyrosine-protein kinase PKDCC {ECO:0000305}; EC=2.7.10.2 {ECO:0000269|PubMed:25171405};AltName: Full=Protein kinase domain-containing protein, cytoplasmic {ECO:0000312|MGI:MGI:2147077};AltName: Full=Protein kinase-like

Provider

SWISS-PROT

Sequence

Polypeptide 492 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pkdcc	protein kinase domain containing, cytoplasmic	43	120	4	8

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:140470 Imuta Y, et al., Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124). Dev Dyn. 2008 Dec 18;238(1):210-222
J:158147 Kinoshita M, et al., The novel protein kinase Vlk is essential for stromal function of mesenchymal cells. Development. 2009 Jun;136(12):2069-79
J:199462 Probst S, et al., The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation. 2013 Apr-Jun;85(4-5):121-30
J:214801 Bordoli MR, et al., A secreted tyrosine kinase acts in the extracellular environment. Cell. 2014 Aug 28;158(5):1033-44