Sequence Detail

ID/Version

Q5PSV9 Q5U4D3 Q6ZQH7 Q52KG1 (UniProt | EBI)

Last sequence update: 2005-01-04
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Mediator of DNA damage checkpoint protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 1707 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mdc1	mediator of DNA damage checkpoint 1	22	98	3	35

Sequence references in MGI

J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:157149 Lee AC, et al., Specific association of mouse MDC1/NFBD1 with NBS1 at sites of DNA-damage. Cell Cycle. 2005 Jan;4(1):177-82
J:192634 Kogo H, et al., HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Genes Cells. 2012 Nov;17(11):897-912
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89