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Sequence Detail
ID/Version
Q5ND04 B2KGG8 Q3TLD8 (UniProt | EBI) Last sequence update: 2005-02-01
Last annotation update: 2025-06-18
Sequence
description
from provider
RecName: Full=Heat shock factor protein 5; Short=HSF 5;AltName: Full=Heat shock transcription factor 5; Short=HSTF 5;AltName: Full=Protein expressed in male leptotene and zygotene spermatocytes 220; Short=MLZ-220;
Provider SWISS-PROT
Sequence
Polypeptide 624 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Hsf5 heat shock transcription factor family member 5 21 98 3 4
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:187568 Kogo H, et al., Screening of genes involved in chromosome segregation during meiosis I: toward the identification of genes responsible for infertility in humans. J Hum Genet. 2010 May;55(5):293-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:347775 Yoshimura S, et al., Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions. Nat Commun. 2024 Apr 29;15(1):3330
J:352587 Barutc AR, et al., Retracted: Heat shock factor 5 establishes the male germ-line meiotic sex chromosome inactivation through regulation of Smarca4. Heliyon. 2023 May;9(5):e15194

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/30/2025
MGI 6.24
The Jackson Laboratory