Sequence Detail

ID/Version

Q5NCH9 (UniProt | EBI)

Last sequence update: 2005-02-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Metabotropic glutamate receptor 6; Short=mGluR6;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 871 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Grm6	glutamate receptor, metabotropic 6	64	99	4	16

Sequence references in MGI

J:40244 Iwakabe H, et al., Impairment of pupillary responses and optokinetic nystagmus in the mGluR6-deficient mouse. Neuropharmacology. 1997 Feb;36(2):135-43
J:48532 Masu M, et al., Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell. 1995 Mar 10;80(5):757-65
J:130134 Morgans CW, et al., Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells. Eur J Neurosci. 2007 Nov;26(10):2899-905
J:146683 Specht D, et al., Effects of presynaptic mutations on a postsynaptic Cacna1s calcium channel colocalized with mGluR6 at mouse photoreceptor ribbon synapses. Invest Ophthalmol Vis Sci. 2009 Feb;50(2):505-15
J:214871 Orlandi C, et al., Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons. Invest Ophthalmol Vis Sci. 2013;54(10):7153-61
J:222352 Xu Y, et al., mGluR6 deletion renders the TRPM1 channel in retina inactive. J Neurophysiol. 2012 Feb;107(3):948-57
J:271244 Ueno A, et al., Lrit1, a Retinal Transmembrane Protein, Regulates Selective Synapse Formation in Cone Photoreceptor Cells and Visual Acuity. Cell Rep. 2018 Mar 27;22(13):3548-3561