Sequence Detail

ID/Version

Q5FWI3 Q3UE15 Q8VE53 Q9QY22 Q6DFZ0 Q3UE98 Q6ZPR7 (UniProt | EBI)

Last sequence update: 2005-03-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Cell surface hyaluronidase {ECO:0000303|PubMed:10767548}; EC=3.2.1.35 {ECO:0000269|PubMed:28246172, ECO:0000269|PubMed:33647313, ECO:0000269|PubMed:37196767};AltName: Full=Cell migration-inducing hyaluronidase 2 {ECO:0000250|UniProtK

Provider

SWISS-PROT

Sequence

Polypeptide 1383 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cemip2	cell migration inducing hyaluronidase 2	14	106	3	71

Sequence references in MGI

J:68964 Scott DA, et al., Refining the DFNB7-DFNB11 deafness locus using intragenic polymorphisms in a novel gene, TMEM2. Gene. 2000 Apr 4;246(1-2):265-74
J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:180896 Smith KA, et al., Transmembrane protein 2 (Tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion development. Development. 2011 Oct;138(19):4193-8
J:242507 Yamamoto H, et al., A mammalian homolog of the zebrafish transmembrane protein 2 (TMEM2) is the long-sought-after cell-surface hyaluronidase. J Biol Chem. 2017 May 05;292(18):7304-7313
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:317425 Tobisawa Y, et al., The cell surface hyaluronidase TMEM2 is essential for systemic hyaluronan catabolism and turnover. J Biol Chem. 2021 Oct 6;297(5):101281