Sequence Detail

ID/Version

Q5FW60 (UniProt | EBI)

Last sequence update: 2005-03-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Major urinary protein 20 {ECO:0000312|MGI:MGI:3651981};AltName: Full=Darcin {ECO:0000303|PubMed:20525243};AltName: Full=Major urinary protein 24 {ECO:0000312|EMBL:ACF70718.1};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 181 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mup20	major urinary protein 20	17	99	6	1

Sequence references in MGI

J:117578 Armstrong SD, et al., Structural and functional differences in isoforms of mouse major urinary proteins: a male-specific protein that preferentially binds a male pheromone. Biochem J. 2005 Oct 15;391(Pt 2):343-50
J:130465 Chamero P, et al., Identification of protein pheromones that promote aggressive behaviour. Nature. 2007 Dec 6;450(7171):899-902
J:144253 Logan DW, et al., Species specificity in major urinary proteins by parallel evolution. PLoS One. 2008;3(9):e3280
J:160965 Roberts SA, et al., Darcin: a male pheromone that stimulates female memory and sexual attraction to an individual male's odour. BMC Biol. 2010;8:75
J:244419 Phelan MM, et al., The structure, stability and pheromone binding of the male mouse protein sex pheromone darcin. PLoS One. 2014;9(10):e108415
J:284984 Liu YJ, et al., Quantitative inheritance of volatile pheromones and darcin and their interaction in olfactory preferences of female mice. Sci Rep. 2017 May 18;7(1):2094
J:285005 Hoffman E, et al., The male sex pheromone darcin stimulates hippocampal neurogenesis and cell proliferation in the subventricular zone in female mice. Front Behav Neurosci. 2015;9:106
J:285012 Roberts SA, et al., Pheromonal induction of spatial learning in mice. Science. 2012 Dec 14;338(6113):1462-5
J:285030 Demir E, et al., The pheromone darcin drives a circuit for innate and reinforced behaviours. Nature. 2020 Feb;578(7793):137-141
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89