Sequence Detail

ID/Version

Q5EBH1 O70407 Q8C2E8 Q6KAR0 (UniProt | EBI)

Last sequence update: 2005-03-15
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Ras association domain-containing protein 5;AltName: Full=New ras effector 1;AltName: Full=Regulator for cell adhesion and polarization enriched in lymphoid tissues; Short=RAPL;

Provider

SWISS-PROT

Sequence

Polypeptide 413 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rassf5	Ras association (RalGDS/AF-6) domain family member 5	22	98	3	9

Sequence references in MGI

J:46202 Vavvas D, et al., Identification of Nore1 as a potential Ras effector. J Biol Chem. 1998 Mar 6;273(10):5439-42
J:79038 Khokhlatchev A, et al., Identification of a novel Ras-regulated proapoptotic pathway. Curr Biol. 2002 Feb 19;12(4):253-65
J:84667 Katagiri K, et al., RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1. Nat Immunol. 2003 Aug;4(8):741-8
J:92574 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Apr 30;11(2):127-35
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113977 Ortiz-Vega S, et al., The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1. Oncogene. 2002 Feb 21;21(9):1381-90
J:137819 Stieglitz B, et al., Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II. EMBO J. 2008 Jul 23;27(14):1995-2005
J:247424 Harjes E, et al., GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1. Structure. 2006 May;14(5):881-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89