Sequence Detail

ID/Version

Q5DTT2 Q3TY69 Q6PE10 B7ZNN7 B2RS07 (UniProt | EBI)

Last sequence update: 2008-05-20
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=PH and SEC7 domain-containing protein 1;AltName: Full=Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6; Short=Exchange factor for ARF6;AltName: Full=Exchange factor for ARF6 A;AltName: Full=Pleckstrin homology

Provider

SWISS-PROT

Sequence

Polypeptide 1024 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Psd	pleckstrin and Sec7 domain containing	7	110	3	7

Sequence references in MGI

J:95306 Decressac S, et al., ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6. EMBO Rep. 2004 Dec;5(12):1171-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:119715 Sakagami H, et al., Somatodendritic localization of EFA6A, a guanine nucleotide exchange factor for ADP-ribosylation factor 6, and its possible interaction with alpha-actinin in dendritic spines. Eur J Neurosci. 2007 Feb;25(3):618-28
J:150660 Sironi C, et al., EFA6A encodes two isoforms with distinct biological activities in neuronal cells. J Cell Sci. 2009 Jun 15;122(Pt 12):2108-18
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89