Sequence Detail

ID/Version

Q52KB6 Q8BXE5 Q3UFQ3 E9QL99 Q80V48 (UniProt | EBI)

Last sequence update: 2013-10-16
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=C2 domain-containing protein 3;AltName: Full=Protein hearty;

Provider

SWISS-PROT

Sequence

Polypeptide 2323 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	C2cd3	C2 calcium-dependent domain containing 3	49	102	3	19

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:142506 Hoover AN, et al., C2cd3 is required for cilia formation and Hedgehog signaling in mouse. Development. 2008 Dec;135(24):4049-58
J:206657 Ye X, et al., C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2164-9
J:213635 Thauvin-Robinet C, et al., The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation. Nat Genet. 2014 Aug;46(8):905-11
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89