Sequence Detail

ID/Version

Q4U2R1 O88473 Q3URH7 Q3TST2 Q5DU32 Q9Z168 Q9QYT1 Q3TS47 Q3UFQ6 Q9Z171 E9PZT6 Q3TRJ8 Q7TPR5 Q80VV7 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000250|UniProtKB:O95714};AltName: Full=HECT domain and RCC1-like domain-containing protein 2;AltName: Full=HECT-type E3 ubiquitin transferase HERC2;

Provider

SWISS-PROT

Sequence

Polypeptide 4836 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Herc2	HECT and RLD domain containing E3 ubiquitin protein ligase 2	33	109	3	36

Sequence references in MGI

J:49046 Lehman AL, et al., A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9436-41
J:53404 Ji Y, et al., The ancestral gene for transcribed, low-copy repeats in the Prader-Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities. Hum Mol Genet. 1999 Mar;8(3):533-42
J:56827 Walkowicz M, et al., Molecular characterization of radiation- and chemically induced mutations associated with neuromuscular tremors, runting, juvenile lethality, and sperm defects in jdf2 mice. Mamm Genome. 1999 Sep;10(9):870-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89