Sequence Detail

ID/Version

Q4JIM5 (UniProt | EBI)

Last sequence update: 2005-08-02
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Tyrosine-protein kinase ABL2; EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 2;AltName: Full=Abelson tyrosine-protein kinase 2;AltName: Full=Abelson-related gene protein;AltName: Full=Tyrosine-protein kinase

Provider

SWISS-PROT

Sequence

Polypeptide 1182 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Abl2	ABL proto-oncogene 2, non-receptor tyrosine kinase	112	107	3	53

Sequence references in MGI

J:51887 Koleske AJ, et al., Essential roles for the Abl and Arg tyrosine kinases in neurulation. Neuron. 1998 Dec;21(6):1259-72
J:73441 Wang Y, et al., The Abl-related gene (Arg) nonreceptor tyrosine kinase uses two F-actin-binding domains to bundle F-actin. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):14865-70
J:89062 Plattner R, et al., Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor. Mol Cell Biol. 2004 Mar;24(6):2573-83
J:116250 Tanis KQ, et al., Two distinct phosphorylation pathways have additive effects on Abl family kinase activation. Mol Cell Biol. 2003 Jun;23(11):3884-96
J:116356 Kain KH, et al., Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes. J Biol Chem. 2001 May 11;276(19):16185-92
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:259787 Gu JJ, et al., Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1. Sci Signal. 2012 Jul 17;5(233):ra51
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89