Sequence Detail

ID/Version

Q4FZC9 Q8C117 Q8BMM1 (UniProt | EBI)

Last sequence update: 2005-08-30
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Nesprin-3;AltName: Full=KASH domain-containing protein 3; Short=KASH3;AltName: Full=Nuclear envelope spectrin repeat protein 3;

Provider

SWISS-PROT

Sequence

Polypeptide 975 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Syne3	spectrin repeat containing, nuclear envelope family member 3	39	99	3	8

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104496 Wilhelmsen K, et al., Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin. J Cell Biol. 2005 Dec 5;171(5):799-810
J:139041 Young KG, et al., Dystonin/Bpag1 is a necessary endoplasmic reticulum/nuclear envelope protein in sensory neurons. Exp Cell Res. 2008 Sep 10;314(15):2750-61
J:140957 Nery FC, et al., TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton. J Cell Sci. 2008 Oct 15;121(Pt 20):3476-86
J:157438 Stewart-Hutchinson PJ, et al., Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness. Exp Cell Res. 2008 May 1;314(8):1892-905
J:187540 Taranum S, et al., Cytoskeletal interactions at the nuclear envelope mediated by nesprins. Int J Cell Biol. 2012;2012:736524