Sequence Detail

ID/Version

Q3V3I2 (UniProt | EBI)

Last sequence update: 2008-07-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Guanine nucleotide-binding protein G(t) subunit alpha-3;AltName: Full=Gustducin alpha-3 chain;

Provider

SWISS-PROT

Sequence

Polypeptide 354 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gnat3	G protein subunit alpha transducin 3	28	105	2	11

Sequence references in MGI

J:36885 Wong GT, et al., Transduction of bitter and sweet taste by gustducin [see comments]. Nature. 1996 Jun 27;381(6585):796-800
J:68225 Huang L, et al., Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. Nat Neurosci. 1999 Dec;2(12):1055-62
J:86070 Grillet N, et al., Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b. J Neurosci. 2003 Nov 19;23(33):10613-21
J:86424 Caicedo A, et al., Role of the G-protein subunit alpha-gustducin in taste cell responses to bitter stimuli. J Neurosci. 2003 Oct 29;23(30):9947-52
J:86747 Kim MR, et al., Regional expression patterns of taste receptors and gustducin in the mouse tongue. Biochem Biophys Res Commun. 2003 Dec 12;312(2):500-6
J:92635 He W, et al., Umami taste responses are mediated by alpha-transducin and alpha-gustducin. J Neurosci. 2004 Sep 1;24(35):7674-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:125201 Margolskee RF, et al., From the Cover: T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15075-80
J:125223 Jang HJ, et al., Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15069-74
J:128673 Ruiz-Avila L, et al., Dominant loss of responsiveness to sweet and bitter compounds caused by a single mutation in alpha -gustducin. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8868-73