Sequence Detail

ID/Version

Q3UXZ9 Q66JZ3 Q3TM94 Q3UMI5 (UniProt | EBI)

Last sequence update: 2007-06-26
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Lysine-specific demethylase 5A; EC=1.14.11.67 {ECO:0000305|PubMed:17320161, ECO:0000305|PubMed:17320163};AltName: Full=Histone demethylase JARID1A;AltName: Full=Jumonji/ARID domain-containing protein 1A;AltName: Full=Retinoblastoma-b

Provider

SWISS-PROT

Sequence

Polypeptide 1690 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kdm5a	lysine demethylase 5A	55	105	3	27

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:137185 Klose RJ, et al., The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell. 2007 Mar 9;128(5):889-900
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:157630 Peng JC, et al., Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell. 2009 Dec 24;139(7):1290-302
J:176119 DiTacchio L, et al., Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock. Science. 2011 Sep 30;333(6051):1881-5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:300695 El Hayek L, et al., KDM5A mutations identified in autism spectrum disorder using forward genetics. Elife. 2020 Dec 22;9:e56883