Sequence Detail

ID/Version

Q3UVR3 Q3TSR6 Q3UFW0 Q8BKA4 Q924U8 Q571D1 A2AW12 (UniProt | EBI)

Last sequence update: 2005-10-11
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Tau-tubulin kinase 2; EC=2.7.11.1;AltName: Full=Protein bartleby;

Provider

SWISS-PROT

Sequence

Polypeptide 1243 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ttbk2	tau tubulin kinase 2	79	98	4	9

Sequence references in MGI

J:68153 Tomizawa K, et al., Tau-tubulin kinase phosphorylates tau at Ser-208 and Ser-210, sites found in paired helical filament-tau. FEBS Lett. 2001 Mar 16;492(3):221-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:197579 Goetz SC, et al., The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis. Cell. 2012 Nov 9;151(4):847-58
J:255486 Agbu SO, et al., The small GTPase RSG1 controls a final step in primary cilia initiation. J Cell Biol. 2018 Jan 2;217(1):413-427