Sequence Detail

ID/Version

Q3USJ8 Q3UQZ2 Q6P9R0 Q80TS2 (UniProt | EBI)

Last sequence update: 2007-02-20
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=F-BAR and double SH3 domains protein 2;AltName: Full=Protein nervous wreck 1 {ECO:0000303|PubMed:23761074, ECO:0000303|PubMed:26567222}; Short=NWK1 {ECO:0000303|PubMed:23761074, ECO:0000303|PubMed:26567222};AltName: Full=SH3 multiple

Provider

SWISS-PROT

Sequence

Polypeptide 740 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fchsd2	FCH and double SH3 domains 2	23	98	3	12

Sequence references in MGI

J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:269545 Almeida-Souza L, et al., A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits. Cell. 2018 Jul 12;174(2):325-337.e14
J:269553 Becalska AN, et al., Formation of membrane ridges and scallops by the F-BAR protein Nervous Wreck. Mol Biol Cell. 2013 Aug;24(15):2406-18
J:283192 Cao H, et al., FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro. PLoS One. 2013;8(2):e56516
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89