Sequence Detail

ID/Version

Q3UMR0 Q91W65 Q6KAU0 Q7TNY8 Q6P1F9 Q8BUD2 (UniProt | EBI)

Last sequence update: 2007-02-06
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Ankyrin repeat domain-containing protein 27;AltName: Full=VPS9 domain-containing protein;AltName: Full=VPS9-ankyrin-repeat protein;

Provider

SWISS-PROT

Sequence

Polypeptide 1048 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ankrd27	ankyrin repeat domain 27	63	98	3	15

Sequence references in MGI

J:92574 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Apr 30;11(2):127-35
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:107001 Zhang X, et al., Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics. J Cell Sci. 2006 Mar 15;119(Pt 6):1053-62
J:197013 Ohbayashi N, et al., The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes. Mol Biol Cell. 2012 Feb;23(4):669-78
J:215880 Burgo A, et al., Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth. EMBO Rep. 2009 Oct;10(10):1117-24
J:215882 Tamura K, et al., Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes. Mol Biol Cell. 2009 Jun;20(12):2900-8
J:230050 Marubashi S, et al., RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes. J Biol Chem. 2016 Jan 15;291(3):1427-40
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89