Sequence Detail

ID/Version

Q3UH99 A0A172Q417 (UniProt | EBI)

Last sequence update: 2005-10-11
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Protein shisa-6 {ECO:0000305};AltName: Full=Cystine-knot AMPAR modulating protein of 52 kDa {ECO:0000303|PubMed:26623514}; Short=CKAMP52 {ECO:0000303|PubMed:26623514};AltName: Full=Shisa family member 6 {ECO:0000305};Flags: Precursor

Provider

SWISS-PROT

Sequence

Polypeptide 525 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Shisa6	shisa family member 6	31	100	2	6

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:236346 Klaassen RV, et al., Shisa6 traps AMPA receptors at postsynaptic sites and prevents their desensitization during synaptic activity. Nat Commun. 2016 Mar 02;7:10682
J:254119 Farrow P, et al., Auxiliary subunits of the CKAMP family differentially modulate AMPA receptor properties. Elife. 2015 Dec 1;4:e09693
J:255015 Schmitz LJM, et al., The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory. Elife. 2017 Dec 4;6:e24192
J:257319 Tokue M, et al., SHISA6 Confers Resistance to Differentiation-Promoting Wnt/beta-Catenin Signaling in Mouse Spermatogenic Stem Cells. Stem Cell Reports. 2017 Mar 14;8(3):561-575
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89