Sequence Detail

ID/Version

Q3UG20 Q3TUY2 Q8BS65 Q6P3B3 Q5FWI1 Q9CVK6 Q8CFX7 Q3SYI5 Q3V410 (UniProt | EBI)

Last sequence update: 2008-06-10
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Inactive histone-lysine N-methyltransferase 2E {ECO:0000305}; Short=Inactive lysine N-methyltransferase 2E {ECO:0000305};AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 5 homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 1868 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kmt2e	lysine (K)-specific methyltransferase 2E	43	99	3	61

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:145445 Heuser M, et al., Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation. Blood. 2009 Feb 12;113(7):1432-43
J:145449 Zhang Y, et al., MLL5 contributes to hematopoietic stem cell fitness and homeostasis. Blood. 2009 Feb 12;113(7):1455-63
J:145579 Madan V, et al., Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5. Blood. 2009 Feb 12;113(7):1444-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89