About   Help   FAQ
Sequence Detail
ID/Version
Q3U108 Q8BI45 Q8R2W1 Q3U0F0 Q8BYB5 Q3TZS4 Q3UDA3 Q3U0S2 Q3UDZ6 (UniProt | EBI) Last sequence update: 2005-10-11
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=AT-rich interactive domain-containing protein 5A; Short=ARID domain-containing protein 5A;
Provider SWISS-PROT
Sequence
Polypeptide 590 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Arid5a AT-rich interaction domain 5A 54 98 3 15
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:182990 Amano K, et al., Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription. Mol Biol Cell. 2011 Apr 15;22(8):1300-11
J:197418 Masuda K, et al., Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9409-14
J:233072 Masuda K, et al., Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA. J Exp Med. 2016 Apr 4;213(4):605-19
J:240577 Zaman MM, et al., Arid5a exacerbates IFN-gamma-mediated septic shock by stabilizing T-bet mRNA. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11543-11548
J:246206 Nyati KK, et al., TLR4-induced NF-kappaB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a. Nucleic Acids Res. 2017 Mar 17;45(5):2687-2703
J:261340 Hanieh H, et al., Arid5a stabilizes OX40 mRNA in murine CD4(+) T cells by recognizing a stem-loop structure in its 3'UTR. Eur J Immunol. 2018 Apr;48(4):593-604
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory