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Sequence Detail
ID/Version
Q3TXX4 E9QMT8 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=Vesicular glutamate transporter 1 {ECO:0000303|PubMed:15103023}; Short=VGluT1 {ECO:0000303|PubMed:15103023};AltName: Full=Brain-specific Na(+)-dependent inorganic phosphate cotransporter {ECO:0000250|UniProtKB:Q62634};AltName: Full=S
Provider SWISS-PROT
Sequence
Polypeptide 560 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 66 131 4 19
Sequence references in MGI J:89958 Wojcik SM, et al., An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size. Proc Natl Acad Sci U S A. 2004 May 4;101(18):7158-63
J:91392 Schafer MK, et al., Molecular cloning and functional identification of mouse vesicular glutamate transporter 3 and its expression in subsets of novel excitatory neurons. J Biol Chem. 2002 Dec 27;277(52):50734-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:105647 Fremeau RT Jr, et al., Vesicular glutamate transporters 1 and 2 target to functionally distinct synaptic release sites. Science. 2004 Jun 18;304(5678):1815-9
J:113744 Yelamanchili SV, et al., Differential sorting of the vesicular glutamate transporter 1 into a defined vesicular pool is regulated by light signaling involving the clock gene Period2. J Biol Chem. 2006 Jun 9;281(23):15671-9
J:122985 Johnson J, et al., Vesicular glutamate transporter 1 is required for photoreceptor synaptic signaling but not for intrinsic visual functions. J Neurosci. 2007 Jul 4;27(27):7245-55
J:201867 Han K, et al., SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties. Nature. 2013 Nov 7;503(7474):72-7
J:256525 Martineau M, et al., VGLUT1 functions as a glutamate/proton exchanger with chloride channel activity in hippocampal glutamatergic synapses. Nat Commun. 2017 Dec 22;8(1):2279
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:311401 Cheret C, et al., Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels. Cell Rep. 2021 Jan 12;34(2):108623
J:324087 Preobraschenski J, et al., Vesicular glutamate transporters use flexible anion and cation binding sites for efficient accumulation of neurotransmitter. Neuron. 2014 Dec 17;84(6):1287-301
J:324193 Preobraschenski J, et al., Dual and Direction-Selective Mechanisms of Phosphate Transport by the Vesicular Glutamate Transporter. Cell Rep. 2018 Apr 10;23(2):535-545

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory