Sequence Detail

ID/Version

Q3TTY5 Q0VBW1 Q61869 (UniProt | EBI)

Last sequence update: 2005-10-11
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Keratin, type II cytoskeletal 2 epidermal;AltName: Full=Cytokeratin-2e; Short=CK-2e;AltName: Full=Epithelial keratin-2e;AltName: Full=Keratin-2 epidermis;AltName: Full=Keratin-2e; Short=K2e;AltName: Full=Type-II keratin Kb2;

Provider

SWISS-PROT

Sequence

Polypeptide 707 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Krt2	keratin 2	34	101	4	13

Sequence references in MGI

J:16846 Herzog F, et al., The large type II 70-kDa keratin of mouse epidermis is the ortholog of human keratin K2e. J Invest Dermatol. 1994 Feb;102(2):165-70
J:33289 Rentrop M, et al., An unusual type-II 70-kilodalton keratin protein of mouse epidermis exhibiting postnatal body-site specificity and sensitivity to hyperproliferation. Differentiation. 1987;34(3):189-200
J:43307 Reichelt J, et al., Out of balance: consequences of a partial keratin 10 knockout. J Cell Sci. 1997 Sep;110(Pt 18):2175-86
J:81301 Fitch KR, et al., Genetics of dark skin in mice. Genes Dev. 2003 Jan 15;17(2):214-28
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:214772 Fischer H, et al., Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation. J Invest Dermatol. 2014 Oct;134(10):2579-88
J:252645 Fischer H, et al., Keratins K2 and K10 are essential for the epidermal integrity of plantar skin. J Dermatol Sci. 2016 Jan;81(1):10-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87